Satoshi Kon worked on several anime classics under Katsuhiro Otomo and Mamoru Oshii, but is most well-known for his own films released by Madhouse: "Perfect Blue", "Millennium Actress", "Tokyo Godfathers" and of course "Paprika". He also made the brilliant 13-episode series "Paranoia Agent". Currently he was working on his new film "The Dreaming Machine" which was scheduled for release next year.
To say he will be missed is an understatement. I think I will revisit "Paprika" tonight, with the commentary track on...
(Thanks go to the Otakon Web Board for spreading the news, and to Peter van der Lugt for alerting me)