Oh joy. Word from Hollywood Reporter is that Eddie Izzard [Oceans Twelve and Mystery Men], everyone's favorite 'Executive Transvestite' and British comedian, will join the cast of Super Ex.
When a regular guy [Luke Wilson] dumps a superhero [Uma Thurman] because of her neediness, she uses her powers to make his life a living hell. IMDB
Suitably, he will play the role of the villain, Professor Bedlam.
Anna Faris [Scary Movie] also joins the cast as Luke Wilson's new love interest.